Department of Senological, Gynecological, Plastic and Reconstructive Surgery - Paris Professor Fabrice Lecuru - Institut Curie
  • Vulvar cancer - Generalities

    Generalities

    Definition

    There are different types of vulvar cancers, depending on the tissue of origin of the cancer:
    epithelial carcinoma (the cells of the most superficial layer of the epidermis)
    basal cell carcinoma (the deepest layer of the epidermis)
    adenocarcinoma (the glandular tissue of the vulva)
    melanoma (the pigment cells of the skin)

    The most common is cancer of epithelial origin, also called squamous cell carcinoma, it represents 80% of cancers.

    Vulvar cancer represents about 5% of cancers in women, and particularly affects elderly women (but not only) who escape regular gynecological follow-up.

    At-risk populations
    Underlying dermatological disease (lichen, Paget's disease); classically older women
    HPV virus (as in cervical and vaginal cancer); classically younger women

    Anatomy
    The term vulva refers to all of the female external genitalia.
    The vulva extends from the pubis to the anus.

    Symptoms
    The main symptoms found are:
    itchy vulva
    wound, ulceration
    bloody or purulent discharge
    pain
    glands in the groin
    leukoplakia (whitish “plaque” appearance)
    “button”
    Black spot
    Difficulty urinating
    Difficulty sitting
    Bad smell

    Evolution
    The cancer is not a cancer at high risk of distant metastasis; it can nevertheless lead to damage to the lymph nodes in the vicinity of the cancer, in particular the inguinal nodes.