Department of Senological, Gynecological, Plastic and Reconstructive Surgery - Paris Professor Fabrice Lecuru - Institut Curie
  • Ovarian cancer - Ongoing trials

    Ongoing trials

    Participation in therapeutic trials (“research protocols”) allows patients to benefit from therapeutic innovations currently being validated.

    These studies are subject to multiple validations guaranteeing their scientific interest and respect for ethics, before being offered to patients.

    The currently open surgical trials are as follows:
    - CHIPOR: benefit of CHIP (IntraPeritoneal ChemoHyperthermia) for platinum-sensitive recurrences of ovarian cancer,
    - CHRONO: surgery after 3 or 6 cycles of chemotherapy, for ovarian cancer,

    The main open drug trials are:
    - GREAT: study of the characteristics of patients with epithelial ovarian cancer based on a BRCA mutation or other genetic abnormalities
    - FIRST: addition of immunotherapy in the treatment of advanced ovarian cancer
    - OREO: re-introduction of olaparib for the treatment of a platinum-sensitive recurrence after exposure to a first PARP inhibitor,
    - BOLD: addition of immunotherapy in platinum-sensitive recurrences of ovarian cancer.